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Autosomal recessive epidermolytic ichthyosis

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Disease definition

A rare, inherited, non-syndromic ichthyosis characterized by congenital, generalized erythroderma with cutaneous blistering and erosions, resembling collodion presentation at birth, replaced by progressive hyperkeratosis later in life without palmoplantar involvement. The ultrastructural pathology consists of sparse keratin filaments and keratin clumps that show a nearly homogeneous, amorphous structure.

ORPHA:512103

Classification level: Disorder

Synonym(s):
  • AREI

Source: PubMed ID 20643494

Prevalence: -

Inheritance: Autosomal recessive

Age of onset:

ICD-10: Q80.8

ICD-11: EC20.03

OMIM: 620707

UMLS: C5437635

A summary on this disease is available in Français, Español, Deutsch, Italiano, Nederlands
Detailed information

Logo ERN: produced/endorsed by ERN(s) Logo FSMR: produced/endorsed by FSMR(s)

Guidelines
Emergency guidelines
Français (2018.pdf) - Orphanet Urgences
Clinical practice guidelines
English (2018) - Br J Dermatol Logo ERN
English (2019) - Br J Dermatol Logo ERN
Patient-Centered Outcome Measures (PCOMs)
Access questionnaires assessing quality of life in this disease (English)
The documents contained in this website are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.