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Polyarticular juvenile idiopathic arthritis

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Disease definition

A rare type of juvenile idiopathic arthritis characterized by arthritis with an onset prior to the age of 16 years persisting for longer than six weeks and affecting at least five joints during the first six months of the disease. Other possible causes of joint inflammation must be excluded. Two subgroups of the disease can be distinguished, based on the presence of absence of rheumatoid factor. Both subgroups are more common in girls and may be associated with mild fever, weight loss, anemia, moderate hepatosplenomegaly, and mild growth retardation.

ORPHA:404580

Classification level: Group of disorders

Synonym(s):
  • Juvenile polyarticular arthritis
  • Juvenile polyarthritis
  • Polyarticular JIA

Prevalence: -

Inheritance: -

Age of onset:

UMLS: C4521004

A summary on this disease is available in Français, Español, Deutsch, Italiano, Nederlands Ελληνικά
Detailed information

Logo ERN: produced/endorsed by ERN(s) Logo FSMR: produced/endorsed by FSMR(s)

General public
Article for general public
Norsk (2016) - PRINTO/PRES
Français (2016) - PRINTO/PRES
עברית (2016) - PRINTO/PRES
Polski (2016) - PRINTO/PRES
Latviešu (2016) - PRINTO/PRES
Deutsch (2016) - PRINTO/PRES
Ελληνικά (2016) - PRINTO/PRES
English (2016) - PRINTO/PRES
Español (2016) - PRINTO/PRES
Nederlands (2016) - PRINTO/PRES
Türkçe (2016) - PRINTO/PRES
ไทย (2016) - PRINTO/PRES
বাংলা (2016) - PRINTO/PRES
Slovenščina (2016) - PRINTO/PRES
Slovenčina (2016) - PRINTO/PRES
Dansk (2016) - PRINTO/PRES
Српски (2016) - PRINTO/PRES
Čeština (2016) - PRINTO/PRES
Русский (2016) - PRINTO/PRES
Hrvatski (2016) - PRINTO/PRES
中文 (2016) - PRINTO/PRES
Română (2016) - PRINTO/PRES
Magyar (2016) - PRINTO/PRES
Italiano (2016) - PRINTO/PRES
العربية (2016) - PRINTO/PRES
Português (2016) - PRINTO/PRES
Guidelines
Emergency guidelines
Français (2025.pdf) - Orphanet Urgences
Clinical practice guidelines
English (2022) - Arthritis Rheumatol
Español (2020.pdf) - Asoc Española de Pediatría
Diagnostic Keys
Français (2022) - Les clés du diagnostic Logo FSMR
Disease review articles
Review article
English (2025) - N Engl J Med
Disability
Disability factsheet
Patient-Centered Outcome Measures (PCOMs)
Access questionnaires assessing quality of life in this disease (English)
The documents contained in this website are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.